Dedicated to the Lord Jesus Christ Who loved us, gave Himself for us, and washed us from our sins in His own Blood; and to the Church, which is His body.

We are not from the world. Through the new birth, we come from God and should constantly remind ourselves of this. 
It is not good to be too "at home" in the world. We are in the world but are not of the world. 
The main reason that God chooses to use those who are nothing by the world's standards, is so no one else can take credit for the great things that are accomplished.
If the Lord used those who had it "all together" in the natural, then they would share the glory that rightfully belongs to God alone. But when the Lord works miraculously through someone who obviously has no talent or ability, then everyone says, "This must be God."
Not only does this keep others from misdirecting the glory that belongs to God, but it keeps the person who God uses from swelling up with pride. One of Satan's greatest weapons against someone who is being used by God is to tempt them to think that the Lord is using them because they possess some great virtue.
God uses "nobodies." If we think we've become "somebody" (in our flesh), then we will quit being used. He will not share His glory with anyone else "......my glory will I not give to another...."Isaiah 42:8.